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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9595d8f140016f8c4b6c82917e4e3adbcef3ff68a0e72114ed42e788eac91003' 
  AND token = 'X1W8eJY/OTEUMNrZ74o/i8pMGshvW9JJsPEJi9Tgv34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}