SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05bb5cf2b35c79ba0e5dd10d3bbdec5c006434a9e233d56dc431fe46477cf67c' 
  AND token = 'JbedcrNlMkcKjhS7zD9ugOpe4Zo4n+8xi6OkUWrsgzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}