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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2d5b57df847014f60ae0e4a00e24f57354670727a38fd3f51bc3835f1296918' 
  AND token = 'Cl9dXA4l8igoPdIIYuPI2lKYCjWCeL0TDg+u+oMUJjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}