SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741b0cc4ef06a160d51b97b65d37bd182f59cb04c69a4a861c63bd489632ed5b' 
  AND token = 'Iy2L6GS86HyfGkKNHDLjxvd8eT83hNk1hOLTKoAGmsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}