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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727e9afc17a6af11ca96e7f157ed92a7d833896d6fe81810daa5c2f0c5d7fbcf' 
  AND token = 'uxGjIKfE3adkqJMdylLYuRP5mSXlGhO7MlnyvZaGS/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}