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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7bc123fd96074e1f7da1f1182d61d2e033c970b1f2e925bc2f215a965c34c5' 
  AND token = 'QfTwceLHFMzqKOnS2ynHcuAcFsH6cuQxYkLsnVmaM8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}