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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d0d59d21afcbd52c488311feb4bd72080ae4957498e3877f2199cb195ef2bc' 
  AND token = 'PqEFq5KSyBkzhFBPpd34yQGMwcftmwUuF0K6yCZAybo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}