SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6621539a1cffef50c3c2d41fd78ee67f9916a46e8dcaa4eef8f57bce9caf54d3' 
  AND token = 'arWJiC9Ckaj+ZUbr8MN+5OUeUWA57Eotgxy91LQswmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}