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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6fba8e40f20887888363f66c00fde1b1ce1718cc3a0cd48c9a784a4c973c3f' 
  AND token = 'ZI6A1nDs/LJqP4KSxgL3IX/ca64UHNlOzyLhBAgvF0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}