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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00ce4fbba884bfd4645fe16714f4e16b4bd7aa6e778d21d1102c8808e4f2d43' 
  AND token = 'TgmKIaBtX50Z+p2WmToMxwJz2BaoENj6IrneFrK2SIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}