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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46a524087ca84b47df85ba4fdb3d7ededd45fe70b225f76603b85a6bf7d72a1' 
  AND token = 'OJzr+lYXcXJWhrnYKL/dIO3i9eadtAQPwFy6B+AaVNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}