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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a36302567e0130f23ca2ebfdbbe8796c9344596363624d7c1d5b5636e7b302c5' 
  AND token = '7EMpWj49TM4O6/7ea5ONFXkTyfWyYJ2lqCKWE+m1Mko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}