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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4449c8d1d346484d792f37cf927392635f02e2349a70dcf53a67140c8e2991e6' 
  AND token = 'l0WKsucQNOqtY40/Uc7k794+a4BCYiZ8KHaLa4gLqgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}