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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2454063149360a47c2fdf96bdc8a5f64b64efd50e9e9e71d21d92ce598cac4b3' 
  AND token = 'R62mvhf4EI4KuGBf0mvecCVzN21lcWbO2Rr0wmRknAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}