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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08d1916e205203c86196193e0f699b78e9dd73408ad325f28df0fe0c92d7230' 
  AND token = 'HKiFXSIBy6zE4qgyLNjl6bMNfiawrp6b0+3WW1l7FnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}