SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e39fdc1d34e428f6bf645753d8545e907cba6f8237ec2214707b476b4ee3bbd' 
  AND token = '8HKxcUDVqOw768/rkN8QfgH95XSTnAjNzh7PZVhcHSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}