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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '855e1cb9c6a4a1868ff3400054e66e13959d2c419b0e4628ca144296b5c1d7aa' 
  AND token = '3f6MMLRO4E8/6/xQ2N2/m+dDCtoYz7q0UzeosHEeU5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}