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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d7580be45b10a2793246b7f38d168c78de31d3d947a6dd0b6eabcd958372b8' 
  AND token = '2H5sdiRNXYCmIZ+HYUozH1dIYgkLd9DRyAKi5iUbVO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}