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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b999779f485feb7748645396e661f0cdfd1e4db27539cedb7e060fdc9abe62fc' 
  AND token = 'hv2vz98XP+Fb/iwrorLY1+HnD3Zv7smz8fAcfgxyoG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}