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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4943d13f611fda95c064a8e08181143cbf3ef3d89a18f0b475babce926b5fbf' 
  AND token = '+C5GXbD6HZ8ZK1a6slVFDXybMmmJHoUjVjiCUEHcj+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}