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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4aee14ba59ee5b1f1a03fb09debd595d12f7286df18216c3f0a697d810cfac9' 
  AND token = 'K1x0Xyo1Wnm2er0JzwUdEhY266sPH3Q0qiHQC+bZDU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}