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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b754cecb82f64780fa2f4fd9e85fd5844f84577dbaeda2497c94f9149f21eabe' 
  AND token = 'Ckmfo+lpPChZCz0w5VF2f2vZT7BS6OqptL+QXjwmvTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}