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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7828e5b58cb37205f69c48da89ec8de709f0a05857d8ae01184c435fb2a19379' 
  AND token = 'iYgH3Jyhk2dz3pxYZuGOziQAAfd6d7L1iRO9R3XQsmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}