SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad064408fd346781bbb38b2990260f13e62d7b5732d550cb0dcda7bf24b8b95' 
  AND token = 'cl1jCv/XJ7VXspuncnPP41wgVHmnDToKBB0Oocvy2PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}