SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22361a43847e0158078065f11f69e00784b1a6e76d455c4ed73a4be393e37eef' 
  AND token = 'SDqL1PaOFvpH9QBiJ+4iSR/cR7m0VcBDJCB0AioWT0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}