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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4746147301d68ff499179e60654c45b852d8da813e95afd5a7a777d7649f8c' 
  AND token = 'fwOQuDvxuuKwdtHfvCnf/5Z24eltUxI4G7H4OImL/A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}