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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80351792d47340f4b2fbaf349d63ad97e1ef24fd7499522ff30fcf6bb7750b9d' 
  AND token = 'RDNy5wP1340FAWdGUl123MkDuioQCG/y2zj3JV7VrCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}