SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654bccdf6e9918e0cf281771b645f12c801b45a9736a734cebba32c4386db5de' 
  AND token = 'jtosOrhxcUtxtED2+/VfoTW2+KKrDtmZ9aZG997EnOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}