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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e29a88360ee94d7a36388224bf4df6073a3612632ed10d59bd5a0af28ccf3f4' 
  AND token = '5VXpNL0W3vxfUaxfAzEL5/IMTz8VmxcqAwn4YB9KKKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}