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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e908bac563c5e3cbd51d04b81971f76eaf790e65f1ddef1cc8e2abcfa171da1e' 
  AND token = 'nDkesFimjnvSTRjPtqi7dzV6gcjbLRL3ga8Jl5+z7KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}