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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d7b62f3d9227b0c91018861f7cd7db0960e9ec1e5dbb5732db236f4049b3a1' 
  AND token = 'pWQ3yLLSc/+Dqqt88VQSljIc0tjeARNyQ2l4EYo2LoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}