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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95302e609b772884b81b4e39416b3d435bb58ac160bc4a258b6dee80acd04bc' 
  AND token = 'RD80ndvDZ/3ay+g35i+pOMdNTFBRATA+aPJnGsL4mfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}