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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1045bf8b71dee3c3381d6658f61cc8321071d11de8b39d789b7b418ec9ecf3' 
  AND token = '6/CqQUEd+uzXPUkzRPZAyERIqu7uWDRiqzyODAlvADc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}