SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45dbd1667771641a75954710a04844b0afacd2918481f49fe3a75f09dc85b8c2' 
  AND token = 'NI10E3Qs8AU9IbQxjTS4oaGz/IvtWLo5ougtIOKETA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}