SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d00e0585666972d86b3b543970482fb1faa56929a42b695da279a84ce62e610' 
  AND token = 'nD3FqkB83qThdyz4YVQRVu4+5GyeipDTXUiG7TEuoPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}