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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca8f8eccf0c244dc350f096ed109278c42bdfd9326bc97343c276303810c8f5' 
  AND token = 'dPtz0IBOFlsv+il6N+b5RMbzcjQyFbICHMrUz4ZOq0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}