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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196144c80f45536cb52b832ba279d6c48db4d082c1cefd0ca7a5e1dec44d502f' 
  AND token = 'EjhHDS3KIoDZ2/3lxYUu2cB8P2fHNTdptbFaeNOYkGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}