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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c76343bea62d036e058c13a508425b0818d41e08c10e5e629021f2d5f66de54d' 
  AND token = '1K3++jnhccAH9Pphegsdd+aUr4YguXs0OfnNAea2was=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}