SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19483394e986b45d52689e593aff19db573f6c848bcf3bc5c2883d77e37eba74' 
  AND token = 'mZ87Nev411e27mvks6oh4fn5CC/znnuU7WB6dmqRw5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}