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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a1a87d2e6df23ec7aea65aa671e802d4ca8a2cd843bc403261657450fe3cd1' 
  AND token = 'ZO8lRkKC65XLkKHa0f0nJuySi5dG3j5rWU9l0LUvz+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00081

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}