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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e995b1a79bb59c26a88dac19e0629f334b02d89b6bb5601d9cd0de282b99b9e' 
  AND token = 'asYx/UU1+i/huO+QrGr7T2vU+pZqDINofXkcZ8xD+AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}