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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2a209649328f84387b625a3cdff1c9fa40a44a348bb0e75c860d2075a9be1f' 
  AND token = 'uI4Nb/4GOXyMEos6rCbz4rStR5EzDJaE9GAniJS1n0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}