SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc3ecdb6cb31d94d8355a72302d4858ad032aebce3a10cdce26544d82e58aeac' 
  AND token = 'y78Qo9WEF3GGnDm+jtFTvitySIKROkLb8fwPng+kasY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}