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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea457d3d724a98e09dfef4b83621b105cf957d6c7e7cb1c45cf1a88f9fc6bdcb' 
  AND token = 'MApdamyNMfc4NC/Mm03wxuns7UXHXQVzJYeOaB8xFQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}