SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f423ec69bb836f5f676b80d20c4182247a329a4ae7d2b1ddb782075fc9e8450b' 
  AND token = 'U2VEbM719eIj/+m9xOXTn5zDcjDFYz4M4kamcNl+Ra8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}