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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591abe7c681d6165fd170f7b6e250e00e64d40356632a0ec4398a00e1c5021f1' 
  AND token = 'n/zWodJoKPdAufBvjh21YN+wlzwt2YsnNOx/fR1YB3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}