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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78a8a36ce06351b32060176f77bd6b5441f97c239974de138864daf0504e8d5' 
  AND token = 'sYMjRTonfO8yrBxJOgnSJZcqQy4e7h/QEwRy7fMjfOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}