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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c556f8a1c7b2cf94380ff741a53c1787d6f1d0a656c176b5a9f4a57cfb96d0a0' 
  AND token = 'CXKh5uOvp3g2aQjRAEk41Ln2ZdsUxk8OVaC4zP5NkB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}