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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de446d6d3c9774ea9e53ca9dbd25796f0da87789b2ac24eae721fafa2043164' 
  AND token = 'WCVrEwnAZNkLi3ZO8yxjcJJOAtofvSu3FHQJ4K2CzOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}