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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c763ffae756f73c2e37ba7c5b394268470497e82967aa9e0575ce81be612f50' 
  AND token = 'S3S9blv0pTM8q45RVFU1gcSui6LkDjA1gaRedaM+DKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}